Faculty of Science

Chemistry Courses

CH110 Fundamentals of Chemistry 0.5

This course is designed to be a first university-level course in chemistry. This course, followed by CH111, prepares students for further studies in all sub disciplines of chemistry as well as laying the chemical foundations for studies in related disciplines such as biology, physics, geography, anthropology and psychology. Topics covered include chemical reactions, stoichiometry, gas laws, quantum theory, the periodic table and chemical bonding.

Prerequisite: OAC Chemistry or Grade 12 U Chemistry.

Exclusion: CH100*, CH101*, CH120.

3 lecture hours, 3 lab/tutorial hours

CH111 Chemical Kinetics and Equilibrium 0.5

This course follows and builds on the concepts from CH110 and prepares students for higher-level studies in the various sub disciplines of chemistry as well other university disciplines. The topics covered in this course are intermolecular bonding, chemical and physical properties of the main group elements, chemistry of carbon, properties of solutions, rates of chemical reactions, equilibria, entropy, free energy and electrochemistry.

Prerequisite: CH110.

Exclusion: CH100*, CH101, CH121.

3 lecture hours, 3 lab/tutorial hours

CH120 Introductory Chemistry 0.5

Identical to CH110, but without the labs.

Prerequisite: OAC Chemistry or Grade 12 U Chemistry

Exclusion: CH100*, CH101*, CH110.

3 lecture hours, 1.5 tutorial hours

CH121 Introduction to Chemical Kinetics and Equilibrium 0.5

Identical to CH111, but without the labs.

Prerequisite: CH110 or CH120.

Exclusion: CH100*, CH101*, CH111.

3 lecture hours, 1.5 tutorial hours

CH202 Organic Chemistry I: Fundamentals 0.5

This course deals with the fundamentals of organic chemistry. The topics considered include carbon compounds and chemical bonds, introduction to functional groups, acids and bases in organic chemistry, nomenclature in organic chemistry, stereochemistry of carbon compounds, ionic reactions: nucleophilic substitutions and elimination, radical reactions, reactions and synthesis of alkanes, alkenes, alkynes, alkyl halides.

Prerequisite: CH110 and CH111.

Exclusion: Exclusion: CH200*, CH201*, CH204.

3 lecture hours, 3 lab hours

CH203 Organic Chemistry II: Structure and Functional Group Chemistry 0.5

This course deals with the structure of organic molecules and the role of functional groups in organic reactions and synthesis. The topics considered include introduction to mass spectrometry, common spectroscopic methods of molecular structural analysis: UV, IR and NMR, aromaticity and aromatic compounds, functional group chemistry and art of organic synthesis, reactions and synthesis of alcohols and phenols, ethers, aldehydes and ketones, carboxylic acids and their derivatives, and amines.

Prerequisite: CH202

Exclusion: CH200*, CH201*, CH205

3 lecture hours, 3 lab hours

CH204 Introductory Organic Chemistry I 0.5

Identical to CH202, but without the labs.

Prerequisite: Both CH110 and CH111 or both CH120 and CH121.

Exclusion: BSc program; CH200*, CH202.

CH205 Introductory Organic Chemistry II 0.5

Identical to CH203, but without the labs.

Prerequisite: CH202 or CH204.

Exclusion: BSc program; CH200*, CH203.

CH212 Thermodynamics 0.5

A development of, and introduction to, the three laws of thermodynamics from a macroscopic approach. The application of thermodynamic concepts to physical and chemical systems, including the study of phase equilibria and chemical equilibria.

Prerequisite: CH110, CH111, MA103 and MA104, or MA105.

Exclusion: CH211, CH311.

3 lecture hours, 1 tutorial hour

CH220* Analytical Chemistry 1.0

Classical wet methods of analysis. Treatment of analytical data. Chemical equilibrium, oxidation-reduction reactions, electrochemistry. Principles and applications of instrumental analysis.

Prerequisite: CH110 and CH111.

3 lecture hours, 4 lab hours

CH225 Inorganic Chemistry I 0.5

Current models of bonding in inorganic chemistry. Molecular Orbital Theory, Introduction to Group Theory and Ligand Field Theory. Hydrogen bonding and other weak interactions, structures and stereochemistry of typical inorganic compounds.

Prerequisite: CH110 and CH111.

CH233 Environmental Atmospheric Chemistry 0.5

The nature and composition of the atmosphere; chemistry of main air pollutants; the ozone layer and chemistry of the chlorofluorocarbons; hydrocarbon emissions and their influence on photochemical smog; greenhouse gases and the greenhouse effect; gaseous inorganic oxide pollutants and acid rain; atmospheric particulate matter and removal methods; importance and methods of atmospheric monitoring; methods for analysis of gaseous pollutants.†

Prerequisite: CH110 and CH111.

CH234 Environmental Aquatic Chemistry 0.5

Chemical principles applied to the study of water. Chemical reactions in aqueous systems, properties and composition of natural waters, redox equilibria in natural waters, micro-organisms as catalysts of aquatic chemical reactions, water pollution and treatment. The laboratory experiments deal with environmental analytical techniques.†

Prerequisite: CH110 and CH111.

2 lecture hours, 3 lab hours

CH236 Industrial Organic Chemistry 0.5

A study of organic processes of importance to the Canadian economy: petroleum, petro-chemicals, plastics and synthetic rubbers, fibres and textiles, pharmaceuticals, etc. Geographic, historical and political factors affecting the location and scale of the various processes.†

Prerequisite: CH202 or CH204 (or permission of the department).

CH250 Bio-organic Chemistry 0.5

In this course the principles of biochemistry are introduced with a chemical emphasis. Topics include: the chemistry of water and biologically relevant aqueous solutions, structure of biomolecules and biopolymers (amino acids, peptides and proteins, nucleotides, DNA and RNA, carbohydrates and polycaccharides, libids and biomembranes), introduction to enzymes and coenzymes.

Prerequisite: CH202.

Co-requisite: CH203.

Exclusion: CH330.

3 lecture hours, 3 lab hours

CH301 Organic Chemistry III: Synthetic Methods 0.5

A study of carbon-carbon bond forming reactions useful in multistep organic synthesis. This will include the chemistry of enolates, conjugate additions and pericyclic processes.†

Prerequisite: CH200* or both CH202 and CH203.

3 lecture hours, 3 lab hours

CH303 Spectroscopic Methods in Organic Structure Elucidation 0.5

A study of the principles and uses of infra-red, ultra-violet, nuclear magnetic resonance and mass spectrometric methods in solving structural and stereochemical problems in organic chemistry.†

Prerequisite: CH200* or both CH202 and CH203.

Exclusion: CH403.

3 lecture hours, 1 tutorial hour

CH306 Physical Organic Chemistry 0.5

Methods of investigating organic reaction mechanisms: kinetics, catalysis, structure-reactivity relationships, isotope studies, solvent effects, orbital symmetry considerations.†

Prerequisite: CH200* or both CH202 and CH203.

CH312 Chemical Kinetics 0.5

Kinetic-molecular theory of gases, introduction to rates of chemical reactions and kinetics of complex reactions.

Prerequisite: CH212.

Exclusion: CH300*/CH350*

CH313 Quantum Chemistry 0.5

Postulates and principles of quantum mechanics. Exact solutions of the Schrodinger Equation for model systems and the hydrogen atom. Molecular orbital and valence bond theory for diatomics.

Prerequisite: CH110, CH111; MA103 and MA104, or MA105.

CH314 Physical Chemistry Laboratory 0.5

Selected experiments in physical chemistry.†

Prerequisite: CH212 and CH220.

Co-requisite: CH312 or CH313.

3 lab hours (over two terms)

CH322 Chromatographic Methods of Instrumental Analysis 0.5

The principles and application of modern chromatographic techniques in chemical analysis.†

Prerequisite: CH220*.

3 lecture hours, 3 lab hours

CH327 Bioinorganic Chemistry 0.5

The inorganic chemistry of biological systems. Areas of study will include metalloproteins (hemoglobin), neurochemistry (electrolytic cell processes), medicinal inorganic chemistry (cis-platinum anticancer drugs) and trace elements in biological systems.†

Prerequisite: CH225.

CH328 Organometallic Chemistry 0.5

An advanced study of inorganic chemistry focusing on organometallic chemistry and catalysis science.†

Prerequisite: CH225.

Exclusion: CH428.

CH329 Inorganic Chemistry II 0.5

Chemistry of the Transition Metal and Main Group elements. Topics covered will include redox, thermodynamic, electronic, magnetic properties and the reactivity of inorganic compounds.†

Prerequisite: CH225.

Exclusion: CH325, CH328.

CH330 Introductory Biochemistry I: Biological Molecules and Aqueous Systems 0.5

The aqueous environment; structure and function of amino acids, proteins, enzymes, carbohydrates, lipids and biological membranes.

Prerequisite: CH200* or both CH202 and CH203.

2 lecture hours, 3 lab hours

CH331 Introductory Biochemistry II: The Chemistry and Energetics of Major Metabolic Pathways 0.5

Thermodynamics and redox potentials of biochemical transformations; metabolism of carbohydrates, lipids and amino acids; vitamins and coenzymes.

Prerequisite: CH330.

2 lecture hours, 3 lab hours

CH350 Biochemistry I: Bioenergetics and Catabolic Pathways 0.5

This course introduces the principles of biochemical thermodynamics and metabolic pathways. Topics include: bioenergetics, introduction to metabolic pathways, catabolic pathways (glycolysis, citric acid cycle, lipid and amino acid oxidation), oxidative phosphorylation and photosynthesis, experimental techniques in biochemistry.

Prerequisite: CH250.

Exclusion: CH331.

3 lecture hours

CH351º Biochemistry Laboratory I 0.25

This course covers experiments related to the Biochemistry I course (CH350). Topics include metabolic enzymes and their function, electrophoresis and column chromatography for separation and purification of biomolecules, electron transport and ATP synthesis in plant (photosynthesis) and animal (oxidative phosphorylation) systems.

Prerequisite: CH250.

Co-requisite: CH350.

3 lab hours

CH352º Biochemistry Laboratory II 0.25

This course covers experiments related to Biochemistry II (CH353) and III (CH354) courses as well as Bioanalytical Chemistry (CH355). Experiments relate to the content of these three biochemical courses and include: techniques for purification and identification of proteins (affinity chromatography, electrophoresis, HPLC), microanalytical methods for qualitative and quantitative analysis of biomolecules with stress on proteins and nucleic acids, isolation and characterization of DNA and biological membranes, structure and function of ion transferring proteins.

Prerequisite: CH351º.

Co-requisite: CH353, CH354, CH355.

3 lab hours

CH353 Biochemistry II: Anabolic Pathways and Membrane Transport 0.5

This course introduces the principles of biosynthesis in living cells and the ways molecules are transported through cell membranes. Topics include: regulation of metabolic pathways, anabolic pathways (carbohydrate, lipid, protein and nucleic acid biosynthesis), transport of biomolecules and ions across cell membranes.

Prerequisite: CH350.

3 lecture hours

CH354 Biochemistry III: Structure and interaction of Proteins and Nucleic Acids 0.5

This course introduces the principles of proteins and nucleic acid structures and the role of these structures in their function. Topics include patterns and motifs in protein and nucleic acid structures, protein and nucleic acid folding, information transfer in proteins and nucleic acids, protein-nucleic acid interactions, protein and nucleic acid characterization and purification.

Prerequisite: CH250.

3 lecture hours

CH355 Bioanalytical Chemistry 0.5

This course introduces the principles of isolation, purification and characterization of biomolecules. Topics include chemical and biochemical analysis of biomolecules, instrumental techniques of analysis, isolation and purification of biomolecules, applications of bioanalytical chemistry in medicine, biotechnology and forensic science.

Prerequisite: CH250, CH220*.

3 lecture hours

CH356 Biotechnology 0.5

This course presents both the theoretical and practical aspects of biotechnology. Topics include history and development of biotechnology, applications of chemistry and biochemistry in biotechnology, fermentation and bioprocessing, biotechnology in pharmaceutical, medical, food, agricultural and environmental sectors.

Prerequisite: CH250.

3 lecture hours

CH401 Chemistry of Aromatic Systems 0.5

The chemistry of non-benzenoid aromatic and simple heterocyclic aromatic systems. Biosynthetic pathways to benzenoid and heterocyclic aromatics.††

Prerequisite: CH301.

CH402 Chemistry of Natural Products 0.5

The chemistry of some selected natural products, including examples from the alkaloids, lignans, terpenes and steroids. Modern methods of structure elucidation and synthesis.††

Prerequisite: CH301.

CH419 Principles of Toxicology 0.5

Introduction to the science of toxicology, with emphasis on chemical aspects of the field.†

Prerequisite: CH330.

CH430 Quantitative Biochemistry 0.5

pH, buffers and titrations; enzyme kinetics and activities; energetics of biochemical processes; radioisotopes.†

Prerequisite: CH330.

CH431 Biochemistry III: Nucleotides and Nucleic Acids 0.5

The chemistry of nucleic acids; DNA and RNA metabolism; ribosomal protein synthesis; the Genetic Code; recombinant DNA technology.†

Prerequisite: CH331 or permission of the department.

CH432 Biophysical Chemistry 0.5

This course explores some of the physical principles underlying the complex nature of living systems. Topics considered include interactions of biomolecules in aqueous environments, structure of biomolecules and main techniques of structure determination (with emphasis on protein structure), bioenergetics and kinetics of biochemical reactions, biological membranes and membrane transport.†

Prerequisite: MA103 (or MA105), CH330 and CH212 (recommended).

CH444 Computational Chemistry 0.5

Introduction to the theory and practice of computational methods in chemistry. Approaches to the approximate solution of the Schrodinger Equation. Fundamentals of semi-empirical and ab initio methods. Lab exercises will be conducted using available computer software.

Prerequisite: CH200* or both CH202 and CH203, CH313.

CH450 Applied Enzymology 0.5

This course expands on previous studies in enzyme chemistry and the application of enzymes in biotechnology. Topics include enzyme nomenclature, principles of enzyme structure and function, enzyme kinetics, biotransformations in chemical synthesis, industrial enzymes, enzymes and biotechnology.

Prerequisite: CH353, CH354.

3 lecture hours

CH451 DNA Science and Technology 0.5

This course is an introduction to the theory of gene expression at the molecular level and applications of DNA recombinant techniques in applied sciences and industries. Topics include genomics and biotechnology, principles of DNA structure and function, gene expression techniques in biotechnology; applications of genetic analysis, nucleic acids and biotechnology.

Prerequisite: BI232, CH354.

3 lecture hours

CH452 Advanced Biochemistry Laboratory 0.5

This course is a one-term experimental component of the two advanced biochemistry courses, CH450 and CH451. Experiments include gene expression techniques, genomics and DNA analysis, enzyme isolation and purification, application of industrial enzymes in medicine and drug design and development.

Prerequisite: CH351º, CH352º.

Co-requisite: CH450, CH452.

5 lab hours

CH453 Molecular Principles of Drug Design 0.5

This course introduces the methodologies underlying the development of novel drugs. Topics include drugs and living organisms, discovery and design of drugs, molecular modeling in drug design, case studies of drug design and development.†

Prerequisite: CH350.

3 lecture hours

CH454 Bioinformatics: Genomics and Proteomics 0.5

This course covers the most recent advances in bioinformatics with special emphasis on genomics and proteomics. Topics include protein and gene databases, principle concepts in genomics and proteomics, techniques in genomics and proteomics.†

Prerequisite: BI232, CH354.

3 lecture hours

CH455 Computational Biochemistry and Molecular Modeling 0.5

This course deals with the basic concepts of computational biochemistry. Topics include: analysis and management of biochemical data, molecular graphics, dynamics of biochemical systems (molecular interactions, enzyme kinetics, metabolism), bioinformatics, introductory computational chemistry, molecular modeling of proteins. The laboratory component includes application of the course content on personal computers with internet access.†

Prerequisite: CH350.

2 lecture hours, 2 lab hours

CH456 Medicinal Chemistry 0.5

This course covers the chemical and biochemical aspects of natural and synthetic drugs. Topics include natural and synthetic drugs, mechanisms of drug action, chemical and biochemical synthesis of drugs.†

Prerequisite: CH250.

3 lecture hours

CH457 Biochemistry in Diagnostics and Therapy 0.5

This course is an introduction to the biochemistry of disease and therapy at the molecular level. The role of enzymology, DNA recombinant technology and chemical and biochemical synthesis in diagnostics are emphasized.†

Prerequisite: CH353, CH354, or permission of the Chemistry Department.

3 lecture hours

CH458 Special Topics in Biochemistry and Biotechnology 0.5

This course introduces the senior students to selected special topics in biochemistry and biotechnology, and develops their skills in scientific presentations and research. The course is a collection of seminars by the instructor on one or a few specialized topics in biochemical sciences and can have one or more general themes.†

Prerequisite: CH353, CH354.

3 lecture hours

CH480 Special Topics in Chemistry 0.5

A detailed examination of a field or topic of interest not covered by the regular program. Consult the Department of Chemistry for current offerings.

Prerequisite: Permission of the department.

Irregular course

CH490* Directed Research in Chemistry 1.0

A detailed study of a topic under faculty supervision including the submission of a formal report.

Prerequisite: Registration status: Year 4 Honours Chemistry (or Honours Chemistry Combination) and permission of both the department and the instructor.

Irregular course

CH495 Directed Studies 0.5

A detailed study of a field or topic of interest in chemistry not available through the regular program.

Prerequisite: Registration status: Year 4 Honours Chemistry (or Honours Chemistry combination) and permission of both the department and the instructor.

Irregular course

Faculty of Science Faculty of Science – Departments, Programs and Courses Chemistry

Official electronic version updated at 10:33 a.m. March 31, 2005